Thermo Fisher Scientific COPB2 Polyclonal Antibody
COPB2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP에 적합하며 인간 및 마우스 반응성. 항원 친화 크로마토그래피로 정제, 액상 형태, 4°C 보관.
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Thermo Fisher Scientific COPB2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000–1:25,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 856–906 of human Coatomer Protein Complex, Subunit Beta 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non–clathrin-coated vesicles, mediating biosynthetic protein transport from the ER via the Golgi to the trans-Golgi network. It is required for budding from Golgi membranes and retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, coatomer recruitment depends on ADP-ribosylation factors (ARFs), small GTP-binding proteins that influence Golgi structural integrity and LDL receptor processing and recycling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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