Thermo Fisher Scientific CLIP170 Polyclonal Antibody
CLIP170 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 인간 및 마우스 반응 예측. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1338 and 1388 of human Cytoplasmic Linker Protein 170 Alpha-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
CLIP170 was initially identified as a new type of intermediate filament-associated protein highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease.
It is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles.
CLIP170 acts with LIS1 to regulate dynein/dynactin binding to microtubules and may influence lamellipodia formation and cell invasion in breast cancer cells by modulating kinesin and IQGAP1 complex interactions.
At least two isoforms of CLIP170 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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