Thermo Fisher Scientific Shiga like-toxin 1 Monoclonal Antibody (13C4)
E. coli 유래 Shiga-like toxin 1을 검출하는 Mouse monoclonal antibody (Clone 13C4). ELISA, Western blot, functional assay에 적합. 단백질 G로 정제된 액상형 항체로, 4°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- MA140277
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Shiga like-toxin 1 Monoclonal Antibody (13C4)
Thermo Fisher Scientific Shiga like-toxin 1 Monoclonal Antibody (13C4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| ELISA | 1:50 |
| Functional Assay | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 13C4 |
| Immunogen | 1B subunit of Shigatoxin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087280 |
Product Specific Information
MA1-40277 detects Shigatoxin 1 from E. coli samples.
It has been successfully used in ELISA, functional assays, and Western blot applications.
The immunogen for MA1-40277 is the 1B subunit of Shigatoxin 1.
Target Information
Shiga-like toxins (SLTs), also called Verotoxins, are produced by enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7, O26:H11, and O111:H8.
These toxins are implicated in hemorrhagic colitis and hemolytic-uremic syndrome, characterized by acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia.
There are several distinct E. coli SLTs:
- SLT-I and SLT-II are produced by EHEC.
- SLT-I and Shiga toxin share 99% amino acid sequence homology.
- SLT-I and SLT-II share about 60% homology and are antigenically distinct.
The toxin protein consists of two domains:
- A polypeptide – inhibits protein synthesis by targeting ribosomes.
- B polypeptide pentamer – binds to the eukaryotic cell receptor globotriaosylceramide (Gb3), leading to receptor-mediated endocytosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.