
Thermo Fisher Scientific PEN2 Polyclonal Antibody
PEN2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 사용 가능하며, 고순도 Affinity Chromatography로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 1–101 of human PEN2/PSENEN (NP_758844.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855639 |
Product Specific Information
Immunogen sequence:
MNLERVSNEE KLNLCRKYYL GGFAFLPFLW LVNIFWFFRE AFLVPAYTEQ SQIKGYVWRS AVGFLFWVIV LTSWITIFQI YRPRWGALGD YLSFTIPLGT P
Target Information
Presenilins, components of the gamma-secretase protein complex, are required for intramembranous processing of type I transmembrane proteins such as Notch and beta-amyloid precursor protein.
Notch signaling mediates diverse developmental cell fates, while beta-amyloid precursor processing generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer’s disease.
This gene encodes a protein essential for Notch pathway signaling and gamma-secretase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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