Thermo Fisher Scientific PR3 Polyclonal Antibody
Thermo Fisher Scientific의 PR3 Polyclonal Antibody는 인간 Proteinase 3(PR3)에 특이적인 토끼 IgG 항체로, Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, 안정적인 PBS/glycerol 버퍼로 장기 보관 가능하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 28–170 of human Proteinase 3/PR3 (NP_0027683) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.75 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855635 |
Product Specific Information
Immunogen sequence:
IVGGHEAQPH SRPYMASLQM RGNPGSHFCG GTLIHPSFVL TAAHCLRDIP QRLVNVVLGA HNVRTQEPTQ QHFSVAQVFL NNYDAENKLN DVLLIQLSSP ANLSASVATV QLPQQDQPVP HGTQCLAMGW GRVGAHDPPA QVL
Target Information
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246).
By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369).
May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-110224_PR3_P24158-1_Rabbit.svg, PA5-110224_PR3_P24158-1_Rabbit_PDP.jpeg)
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