Thermo Fisher Scientific GPR120 Polyclonal Antibody
GPR120 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 333–377 of human FFAR4 (NP_859529.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.7 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914230 |
Product Specific Information
Positive test controls include:
- HT-29
- BxPC-3
- RAW264.7
- Mouse large intestine
- Rat large intestine
- Rat small intestine
Immunogen sequence:
NPILYNMTLC RNEWKKIFCC FWFPEKGAIL TDTSVKRNDL SIISG
Target Information
An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
Activating ligands induce conformational changes leading to signaling via G-proteins and downstream effectors.
Negative regulation of GPCRs plays a crucial role in cellular physiology and is a key area in pharmacological research.
Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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