Thermo Fisher Scientific CD98 Recombinant Rabbit Monoclonal Antibody (048)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Higher specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

This antibody has specificity for Mouse SLC3A2.

Target Information

CD98 (4F2) is a type II transmembrane glycoprotein that serves as the heavy chain of heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bonds, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells. It also interacts with beta1 integrins, increasing their affinity for ligands.

In addition to its role in amino acid transport, CD98 is involved in cell fusion and activation, and plays a role in regulating cellular differentiation, growth, and apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.