Thermo Fisher Scientific SOAT2 Monoclonal Antibody (OTI2D3), TrueMAB
Human SOAT2 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, IHC(P)에서 1:150 희석 비율로 사용 가능. 무보존제, 동결건조 형태이며 PBS/trehalose buffer에 저장. 콜레스테롤 에스터화 관련 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–120 of human SOAT2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
SOAT2 (Sterol O-Acyltransferase 2) is a membrane-bound enzyme localized in the endoplasmic reticulum, responsible for producing intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. These esters are stored as cytoplasmic lipid droplets.
The enzyme plays a role in intestinal cholesterol absorption and in the assembly/secretion of apolipoprotein B-containing lipoproteins such as VLDL.
Several alternatively spliced transcript variants have been described, though their full-length forms are not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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