Thermo Fisher Scientific A2BP1 Polyclonal Antibody
A2BP1(RBFOX1) 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB 및 IHC(P) 실험에 적합. 인간, 마우스, 랫트 반응성. 액상 형태로 -20°C 보관. Affinity chromatography로 정제된 고순도 항체.
- 카탈로그번호
- PA5103622
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RBFOX1 (Accession Q9NWB1), corresponding to amino acid residues A22–H72 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852958 |
Product Specific Information
Antibody detects endogenous levels of total FOX1.
Target Information
Ataxin-2 binding protein 1 (A2BP1) possesses an RNP motif highly conserved among RNA-binding proteins. It binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene, which causes familial neurodegenerative diseases. Both ataxin-2 binding protein 1 and ataxin-2 are localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been identified, though some remain incompletely characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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