Thermo Fisher Scientific WT1 Polyclonal Antibody

Thermo Fisher Scientific WT1 Polyclonal Antibody

Applications

• Western Blot (WB): 1–3 µg/mL
• Tested in Peptide ELISA (antibody detection limit dilution: 1:32,000)

Product Specifications

Target Information

The Wilms Tumor 1 (WT1) gene encodes one of the WPP domain-interacting proteins required for RanGAP nuclear envelope association in root tip cells.
Ran GTPase is essential for nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly.
The cytoplasmic RanGTPase activating protein (RanGAP) helps establish a functional RanGTP/RanGDP gradient across the nuclear envelope.
In Arabidopsis thaliana, RanGAP association requires CC-TMD and WPP domain-interacting proteins (WIPs). WT1 and WIT2 are a second family of CC-TMD proteins distinct from WIPs, crucial for RanGAP nuclear envelope association in root tip cells.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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