Thermo Fisher Scientific Caspase 1 p10 Polyclonal Antibody
Caspase 1 p10 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. Human, Mouse, Rat 반응성. 고순도 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C 이하에서 안정적.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Caspase 1 p10 subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.59 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913102 |
Product Specific Information
- Store as concentrated solution.
- Centrifuge briefly prior to opening vial.
- For short-term storage (1–2 weeks), store at 4°C.
- For long-term storage, aliquot and store at -20°C or below.
- Avoid multiple freeze-thaw cycles.
Target Information
Caspase-1 (CASP1) is a thiol protease that cleaves IL-1 beta between Asp and Ala, leading to release of the mature cytokine involved in inflammatory processes. CASP1 plays a key role in pathogen defense, activates sterol regulatory element binding proteins (SREBPs), and promotes apoptosis. Upon inflammasome activation during DNA virus infection, CASP1 controls antiviral immunity through cleavage and inactivation of CGAS.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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