Thermo Fisher Scientific KCNN3 Polyclonal Antibody
KCNN3 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 KCNN3에 반응하며 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 장기 보관 시 -20°C에서 보관.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human KCNN3. Recombinant protein control fragment (Product #RP-106751) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665070 |
Product Specific Information
Immunogen sequence:
NLIEAETEGQP LQLFSPSNPP EIVISSREDN HAHQTLLHHP NATHNHQHAG TTASSTTFPK ANKRK
- Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 95%
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels.
KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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