Thermo Fisher Scientific KCNN3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human KCNN3. Recombinant protein control fragment (Product #RP-106751). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KCNN3,uniProtId:Q9UGI6-1,ncbiNodeId:9606,antigenRange:197-262,antigenLength:731,antigenImageFileName:PA5-66058_KCNN3_Q9UGI6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66058_KCNN3_Q9UGI6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2665070

Product Specific Information

Immunogen sequence: NLIEAETEGQP LQLFSPSNPP EIVISSREDN HAHQTLLHHP NATHNHQHAG TTASSTTFPK ANKRK

Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.

Target Information

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.