
Thermo Fisher Scientific RHBDD1 Polyclonal Antibody
Rabbit에서 유래한 RHBDD1 단백질에 특이적인 polyclonal antibody입니다. 비결합형 액상 형태로 제공되며, 0.2 mg/mL 농도입니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다. 연구용으로만 사용 가능합니다.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RHBDD1 (antigen range: 42–101, length: 315 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664199 |
Product Specific Information
Immunogen sequence:
FLNPQKPLYSS CLSVEKCYQQ KDWQRLLLSP LHHADDWHLY FNMASMLWKG INLERRLGS
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 83%
Target Information
The Rhomboid family of proteins consists of widely conserved polytopic membrane serine proteases involved in growth and development.
RHBDD1 is highly expressed in the testis and participates in the cleavage of BIK, a proapoptotic member of the Bcl-2 family.
Overexpression or suppression of RHBDD1 in 293 cells modulates BIK-mediated apoptosis.
In GC-1 spermatogonia cells, RNAi-mediated suppression of RHBDD1 expression causes loss of survival and differentiation ability in mouse seminiferous tubules, suggesting a role in mammalian spermatogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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