Thermo Fisher Scientific LARGE Polyclonal Antibody
LARGE 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human LARGE (proprietary sequence) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736081 |
Product Specific Information
- Positive Control: Mouse liver
- Predicted Reactivity: Human (100%), Rhesus Monkey (100%), Bovine (99%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The LARGE gene encodes a member of the N-acetylglucosaminyltransferase gene family. It participates in the glycosylation of alpha-dystroglycan and may contribute to glycoprotein and glycosphingolipid sugar chain synthesis. Mutations in this gene cause MDC1D, a congenital muscular dystrophy characterized by severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing results in two transcript variants encoding the same protein.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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