Thermo Fisher Scientific NDRG1 Polyclonal Antibody, Biotin
NDRG1 단백질을 인식하는 Biotin 결합 다클론 항체로, Western blot 및 IHC에 사용 가능. 인간 시료 반응성, Goat 유래 IgG. 고순도(암모늄 황산 침전), TBS/BSA buffer 보존. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 2–4 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence GNSAGPKSMEVSC (aa 382–394) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932688 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth, and differentiation. Its defect causes Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet.
NDRG1 plays a growth inhibitory role and serves as a marker of differentiation. It is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon, and the cells that border the lumen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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