Thermo Fisher Scientific LOX-1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• This antibody can block receptor-ligand interaction in a functional ELISA assay.
• In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant mouse LOX-1 is observed.
• Reconstitute at 0.2 mg/mL in sterile PBS.
• Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

LOX-1 (lectin-like oxidized LDL receptor-1) is a 40–50 kDa type II membrane glycoprotein, classified as a class E scavenger receptor. It is expressed by endothelial cells, macrophages, activated platelets, and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized LDL (oxLDL), hypochlorite-modified HDL, aged/apoptotic cells, activated platelets, and bacteria, reflecting its versatile physiological functions.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.