Thermo Fisher Scientific LILRB4 Polyclonal Antibody
Human LILRB4 단백질을 인식하는 Goat Polyclonal 항체로 Western blot 및 Flow Cytometry에 적합. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. PBS(5% trehalose) 완충액에 보관하며, 재구성 후 -20°C에서 보관 권장.
- 카탈로그번호
- PA547314
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human LILRB4/CD85k/ILT3 (Pro17–His257) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606521 |
Product Specific Information
- In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) ILT4 and rhILT5 is observed, and less than 5% cross-reactivity with recombinant human ILT2 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, located at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors, containing two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells, binds to MHC class I molecules on antigen-presenting cells, and transduces a negative signal that inhibits immune response stimulation. It may also function in antigen capture and presentation. This receptor helps regulate inflammatory responses and cytotoxicity to limit autoreactivity. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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