Thermo Fisher Scientific ATG4A Polyclonal Antibody
ATG4A 단백질을 인식하는 Sheep 유래 Polyclonal Antibody. 인간 및 마우스 시료에 반응하며, WB와 IHC에 적합. 합성 펩타이드 항원으로 제작된 비결합형 항체로, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:3,000 | - |
| Immunohistochemistry (IHC) | 1:200–1:3,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human ATG4A conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in mouse.
- Specificity: ATG4A.
Target Information
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. It is essential for cell homeostasis and remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced autophagy levels have been observed in some malignant tumors, suggesting a role in controlling unregulated cell growth in cancer.
This gene encodes a member of the autophagin protein family, designated as part of the C-54 family of cysteine proteases. Distinct transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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