Thermo Fisher Scientific NF-kappaB1 Polyclonal Antibody
NF-kappaB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 인간 시료 반응성으로 세포 성장 및 염증 관련 연구에 적합.
- 카탈로그번호
- A301819Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NF-kappaB1 Polyclonal Antibody
Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
NF-kB is a nuclear transcription factor activated by various extracellular and intracellular stimuli such as cytokines, UV radiation, stress, injury, and bacterial or viral products. It regulates cellular events including cell growth, differentiation, proliferation, apoptosis, and inflammation.
NFKB1 (p50), a 50 kDa functional subunit of NF-kB, belongs to the Rel protein family and is synthesized as a p105 precursor protein. It includes an N-terminal conserved RHD region containing nuclear localization signal, DNA-binding, and dimerization domains.
NFKB1 (p50) forms homodimers or heterodimers with p65, creating the functional NF-kB factor. It directs nuclear translocation and DNA-binding of NF-kB.
Pathological roles of NF-kB have been implicated in AIDS, hematogenic cancer cell metastasis, and rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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