Thermo Fisher Scientific GEF-H1 Monoclonal Antibody (GT336)
GEF-H1 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, WB 및 ICC/IF 실험에 적합합니다. Human, Mouse, Rat에 반응하며, Protein G로 정제된 액상 형태입니다. 세포 신호 조절 및 Rho GTPase 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT336 |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human GEF-H1. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735201 |
Product Specific Information
- Positive Control: 293T, A431, HeLa, C8D30, BCL-1, Raw264.7, C2C12, Rat-2, 3A6
- Predicted Reactivity: Dog (92%), Pig (96%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP.
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli via G protein coupled receptors.
GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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