
Thermo Fisher Scientific CD19 Monoclonal Antibody (OTI2F6), TrueMAB
인간 CD19 단백질을 인식하는 Mouse IgG2a 단일클론 항체. Western blot, ICC/IF, Flow cytometry에 적합. 비결합형 액상 포맷으로 제공되며, 고순도 친화 크로마토그래피 정제. B세포 관련 연구 및 백혈병 표지 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50 |
| Miscellaneous PubMed (Misc) | - |
Publications: View 1 publication
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F6 |
| Immunogen | Full length human recombinant protein of human CD19 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats:
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on nearly all peripheral B cells and certain myeloid leukemia cells. CD19 serves as a signal-amplifying coreceptor for the B cell receptor (BCR) and can also signal independently. It plays a central role in regulating B cell activation and proliferation. Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression may cause B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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