Thermo Fisher Scientific HTR7 Polyclonal Antibody
HTR7 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 2–3 µg/mL 농도로 사용 가능. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. 5-HT7 수용체 연구에 적합하며, 신경 및 혈관 관련 연구용으로 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from C-terminus of human 5HT7 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550699 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon (100%)
- Monkey (95%)
- Marmoset (85%)
Target Information
5-HT7 Receptor is a Serotonin Receptor involved in regulating circadian rhythm and mediating smooth-muscle relaxation in the vasculature and gastrointestinal tract.
This receptor has been implicated in depression, autism, and other neuropsychiatric disorders.
Three protein isoforms have been documented:
- Isoform a: 445 aa
- Isoform b: 432 aa
- Isoform d: 479 aa
Expression reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel.
An EST has been isolated from a testis library.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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