Thermo Fisher Scientific HTR7 Polyclonal Antibody
HTR7 폴리클로날 항체로 인간 5-HT7 세로토닌 수용체를 특이적으로 인식합니다. 면역조직화학(IHC) 및 면역세포화학(ICC/IF)에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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- PA533314
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 13 µg/mL |
| Immunocytochemistry (ICC/IF) | 13 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminus of human 5HT7 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550698 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human: 100%
- Gorilla: 94%
- Gibbon: 88%
- Monkey: 81%
Target Information
5-HT7 Receptor is a serotonin receptor involved in regulating circadian rhythm and mediating smooth-muscle relaxation in vasculature and the GI tract. It has been implicated in depression, autism, and other neuropsychiatric disorders.
Three protein isoforms have been documented:
- Isoform a: 445 aa
- Isoform b: 432 aa
- Isoform d: 479 aa
Expression has been reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel. An EST has been isolated from a testis library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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