Thermo Fisher Scientific TL1A Polyclonal Antibody
Rabbit polyclonal antibody against human TL1A (VEGI) for WB and ELISA. Recognizes C-terminal peptide of TL1A. Supplied as liquid at 0.25 mg/mL, stored at -20°C. For research use only.
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- 343900
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the C-terminal sequence of human VEGI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Storage Conditions | -20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_2533168 |
Target Information
The protein encoded by this gene is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It is abundantly expressed in endothelial cells, but not in B or T cells. Expression is inducible by TNF and IL-1α. This cytokine binds to receptors TNFRSF25 and TNFRSF21/DR6, activates NF-κB and MAP kinases, and induces apoptosis in endothelial cells. It also inhibits endothelial cell proliferation, functioning as an angiogenesis inhibitor. An additional isoform from an alternatively spliced transcript variant has been reported, though its sequence is undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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