Thermo Fisher Scientific WDR5 Chimeric Recombinant Rabbit Monoclonal Antibody (RAB-C223)
WDR5 단백질을 인식하는 재조합 토끼 단클론 항체로 인간 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry 등 다양한 응용에 적합합니다. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적인 액상 형태로 제공됩니다.
- 카탈로그번호
- MA548332
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- pk
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Thermo Fisher Scientific WDR5 Chimeric Recombinant Rabbit Monoclonal Antibody (RAB-C223)
Applications 및 Tested Dilution
| Application | Tested Dilution | 참고 |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Flow Cytometry (Flow) | 1:100 | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| ChIP assay (ChIP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RAB-C223 |
| Immunogen | Recombinant antibody (rAb) phage display recognizing WDR5 protein under non-denaturing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074774 |
Product Specific Information
- Specificity: Recognizes WDR5 (WD repeat-containing protein 5), binding to folded domain (amino acids 1–334).
- Function: WDR5는 히스톤 변형에 관여하는 단백질입니다.
Target Information
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Acts as a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruitment of EGLN1/PHD2 to the HSP90 pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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