
Thermo Fisher Scientific Adiponectin Polyclonal Antibody
Rat Adiponectin을 인식하는 goat polyclonal antibody로, WB, IHC(F), ICC/IF에 사용 가능. Mouse 및 human Adiponectin에 부분 교차 반응. 항원 친화 크로마토그래피로 정제된 동결건조 형태. 연구용으로만 사용.
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Thermo Fisher Scientific Adiponectin Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant rat Adiponectin/Acrp30 Ile19–Asn244 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576236 |
Product Specific Information
- In Western blots, approximately 45% cross-reactivity with recombinant mouse Adiponectin and 35% with recombinant human Adiponectin are observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates lipid and glucose metabolism. It plays roles in homeostasis and obesity. Decreased levels are associated with obesity, insulin resistance, and hyperinsulinemia (type 2 diabetes). In mice, adiponectin improves insulin signaling and activates AMP kinase and PPAR-alpha, promoting fatty acid transport and oxidation in skeletal muscle, reducing intramyocellular lipid levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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