Thermo Fisher Scientific Endothelin 2 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: MVSVPTTWCS VALALLVALH EGKGQAAATL EQPASSSHAQ GTHLRLRRCS
• Storage guidance:
  • Short term: 2–8°C (up to 1 week)
  • Long term: -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  • Human: 100%
  • Mouse: 100%
  • Rabbit: 93%
  • Rat: 93%

Target Information

Endothelins are endothelium-derived vasoconstrictor peptides. Endothelin 2 (ET-2) is encoded by the EDN2 gene in humans. The secreted peptide (~2 kDa, 21 amino acids) is generated from a precursor (~20 kDa) and acts as a ligand for endothelin receptors, modulating various cell signaling pathways.
Diseases associated with endothelins include aortic disease and patent ductus arteriosus.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.