Thermo Fisher Scientific CK1 alpha Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
HQYDYTFDWT MLKQKAAQQA ASSSGQGQQA QTPTGKQTDK TKSNMKGF

• For short-term use: store at 2–8°C up to 1 week.
• For long-term storage: store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology: Cow 79%; Dog 100%; Guinea Pig 100%; Horse 100%; Human 100%; Mouse 100%; Rat 100%; Zebrafish 100%.

Target Information

Gene: CSNK1A1 (CK1 alpha 1)
CK1 alpha is a member of the casein kinase I (CKI) family, encoding serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric (25–55 kDa) and localized in nuclei, cytoplasm, and membranes of eukaryotic cells.

• Participates in Wnt signaling
• Phosphorylates CTNNB1 at Ser-45
• May phosphorylate PER1 and PER2
• Plays a role in chromosome segregation during mitosis

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.