Thermo Fisher Scientific Epo Monoclonal Antibody (BGN/6C7)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1:500,000-1:2,000,000

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

BGN/6C7

Immunogen

R-DNA.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4°C or -20°C if preferred

Shipping conditions

Wet ice

RRID

AB_930728

Product Specific Information

Mouse anti Human erythropoietin antibody, clone KT37 recognizes human erythropoietin (EPO), a approximately 30 kDa glycoprotein hormone primarily secreted by the kidney that stimulates bone marrow erythropoiesis in response to hypoxia or anemia.

Target Information

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.