Thermo Fisher Scientific MT-ND4L Polyclonal Antibody
MT-ND4L 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. Human 및 Mouse 시료에 반응하며, 에너지 대사 관련 Complex I 연구에 적합. PBS/glycerol buffer에 보관, -20°C 저장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MT-ND4L (Accession P03901), corresponding to amino acid residues M1–L49 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853285 |
Product Specific Information
Antibody detects endogenous levels of total MT-ND4L.
Target Information
NADH:ubiquinone oxidoreductase (complex I) is a multiprotein complex located in the inner mitochondrial membrane. It plays a key role in energy metabolism by transporting electrons from NADH to ubiquinone, coupled with proton translocation across the mitochondrial membrane.
Human complex I comprises 41 subunits; subunits 1–7 are encoded by mitochondrial genes, while others are nuclear encoded.
NADH dehydrogenase subunit 4L (ND4L) is part of the hydrophobic segment of Complex I. Mutations in ND4 are associated with Leber hereditary optic neuropathy, a rare disorder causing central vision loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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