Thermo Fisher Scientific MMP-28 Polyclonal Antibody
인간 MMP-28 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, 세포외 공간 및 기질 연구에 활용 가능. 4°C 단기 보관, 장기 보관 시 -20°C 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to inter-segment of human MMP28 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Positive control: Human placenta, human testis lysate
- Cellular location: Secreted, extracellular space, extracellular matrix
Target Information
Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein belonging to the peptidase M10A family. Matrix metalloproteinases are involved in extracellular matrix breakdown, essential for tissue remodeling, reproduction, and embryonic development. Epilysin, produced by proliferating keratinocytes, mediates casein degradation and is upregulated following skin injury, suggesting roles in tissue repair and homeostasis. It may also function in the nervous system, as incubation with rat embryonic brain tissue leads to myelin protein degradation. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation, indicating a conserved role in neural development and modulation of the axonal-glial extracellular environment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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