Thermo Fisher Scientific CD100 Polyclonal Antibody
Thermo Fisher Scientific의 CD100 Polyclonal Antibody는 인간 CD100(SEMA4D) 단백질을 인식하는 토끼 유래 항체로, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA522803
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 147–158 of the human CD100 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154182 |
Product Specific Information
- Suggested positive control: antigen standard for SEMA4D (transient overexpression lysate).
Target Information
Semaphorins are neuronal chemorepellants that guide pioneering neurons during nervous system development.
CD100 (also known as Semaphorin 4D) is a 150 kDa homodimer that induces B cell aggregation and improves viability in vitro.
It modulates CD40–CD40L signaling by enhancing B cell aggregation and survival while downregulating CD23 expression.
CD72 serves as a lymphocyte receptor for CD100, regulating B cell signaling.
CD100 is expressed on resting and PHA-stimulated T cells, weakly on NK cells, EBV-transformed B cells, monocytes, and T cell lines, and more strongly on activated T and B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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