
Thermo Fisher Scientific Geminin/DNA Replication Inhibitor Monoclonal Antibody (GMNN/4033)
Geminin 단백질을 표적으로 하는 GMNN/4033 단클론 항체로 DNA 복제 억제 연구에 적합함. 인간 시료 반응성, 단클론 마우스 IgG1 타입. 다양한 면역조직화학(IHC) 응용 가능. 단백질 A/G로 정제된 액상 형태로 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GMNN/4033 |
| Immunogen | Recombinant fragment (around aa71–202) of human GMNN protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GMNN inhibits DNA replication by preventing the incorporation of MCM complex into the prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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