Thermo Fisher Scientific Geminin/DNA Replication Inhibitor Monoclonal Antibody (GMNN/4033)
Geminin 단백질을 표적하는 GMNN/4033 클론의 마우스 단클론 항체. 인간 시료에 반응하며, IHC 및 Peptide Array에 적합. DNA 복제 억제 연구용으로 사용. 1 mg/mL 농도의 액상 형태, 단백질 A/G 정제, PBS 버퍼에 보존.
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Thermo Fisher Scientific Geminin/DNA Replication Inhibitor Monoclonal Antibody (GMNN/4033)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GMNN/4033 |
| Immunogen | Recombinant fragment (around aa71–202) of human GMNN protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
GMNN inhibits DNA replication by preventing the incorporation of the MCM complex into the prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase–anaphase transition permits replication in the succeeding cell cycle.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: 51053-MSM3-P1ABX_GMNN_O75496-1_House_mouse_PDP.jpeg)
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배송/결제/교환/반품 안내
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