Thermo Fisher Scientific Kir3.1 (KCNJ3) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human KCNJ3(Accession P48549), corresponding to amino acid residues L161-L211. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Kir3.1 (KCNJ3),uniProtId:P48549-1,ncbiNodeId:9606,antigenRange:161-211,antigenLength:501,antigenImageFileName:PA5-99646_Kir3.1_KCNJ3_P48549-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99646_Kir3.1_KCNJ3_P48549-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818579

Product Specific Information

Antibody detects endogenous levels of total GIRK1/KIR3.1/KCNJ3.

Target Information

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.