Thermo Fisher Scientific KCNT1 Polyclonal Antibody
KCNT1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간, 생쥐, 랫트 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
- 카탈로그번호
- PA599644
- 판매단위
- pk
카탈로그
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Applications
Tested Application
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KCNT1 (Accession Q5JUK3), corresponding to amino acid residues I1019–G1069 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818577 |
Product Specific Information
This antibody detects endogenous levels of total KCNT1.
Target Information
Potassium channels represent a complex class of voltage-gated ion channels with diverse physiological roles, including:
- Regulation of neurotransmitter release and heart rate
- Control of insulin secretion and neuronal excitability
- Mediation of epithelial electrolyte transport and smooth muscle contraction
The KCNT1 gene encodes a sodium-activated potassium channel subunit involved in ion conductance and developmental signaling pathways. Mutations in this gene are associated with early-onset epileptic disorders such as malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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