Thermo Fisher Scientific KCNT1 Polyclonal Antibody

Applications

Tested Application

• Western Blot (WB): 1:1,000 dilution

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total KCNT1.

Target Information

Potassium channels represent a complex class of voltage-gated ion channels with diverse physiological roles, including:

• Regulation of neurotransmitter release and heart rate
• Control of insulin secretion and neuronal excitability
• Mediation of epithelial electrolyte transport and smooth muscle contraction

The KCNT1 gene encodes a sodium-activated potassium channel subunit involved in ion conductance and developmental signaling pathways. Mutations in this gene are associated with early-onset epileptic disorders such as malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.