Thermo Fisher Scientific Emerin Polyclonal Antibody
Thermo Fisher Scientific의 Emerin Polyclonal Antibody는 인간 Emerin 단백질(1–50번 잔기 영역)에 특이적으로 반응하는 토끼 IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of human Emerin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight. The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is essential for DNA repair of UV-induced damages. Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA, cleaving model DNA bubble structures near the junction of unpaired DNA with a duplex region. A 29-amino acid region of human XPG (residues 981–1009) contains the PCNA binding activity, and Arg992 is crucial for this interaction. Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, XPA and XPG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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