Thermo Fisher Scientific Olig2 Polyclonal Antibody
Olig2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA, IP 등에 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드(aa 1-50) 면역원 사용. 액상 형태로 -20°C 보관. 연구용 전용 시약.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acid region 1–50 of human Olig2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, containing 0.5% BSA and 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a basic helix-loop-helix transcription factor expressed in oligodendroglial tumors of the brain. The protein regulates ventral neuroectodermal progenitor cell fate and is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. The gene is located on chromosome 21, a region linked to learning deficits in Down syndrome.
Tissue specificity: Expressed in the brain, particularly in oligodendrocytes. Strongly expressed in oligodendrogliomas; weak to moderate expression in astrocytomas; variable expression in glioblastomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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