Thermo Fisher Scientific Olig2 Polyclonal Antibody
Olig2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ELISA, IP 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도 Affinity chromatography로 정제되었습니다. 신경세포 분화 연구 및 종양 분석에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to Human Olig2 amino acids 136–156 (Sequence: PYAHGPSVRKLSKIATLLLAR). The peptide was post-synthetically modified for high antigenicity and conjugated to a carrier protein using a hetero-bifunctional cross linker. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a basic helix-loop-helix transcription factor expressed in oligodendroglial tumors of the brain. The protein regulates ventral neuroectodermal progenitor cell fate and is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. The chromosomal region (chromosome 21) may also play a role in learning deficits associated with Down syndrome.
Tissue specificity: Expressed in the brain, particularly in oligodendrocytes. Strongly expressed in oligodendrogliomas; weak to moderate in astrocytomas; variable in glioblastomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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