Thermo Fisher Scientific KCNAB3 Polyclonal Antibody
KCNAB3 단백질을 표적으로 하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. IHC(P) 실험에 적합하며, 액상 형태로 제공. -20°C에서 보관하며 뇌 조직에서 높은 발현을 보이는 KCNAB3 연구에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the C-terminal region of human KCNAB3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556091 |
Target Information
Voltage-gated K⁺ channels in the plasma membrane control the repolarization and frequency of action potentials in neurons, muscles, and other excitable cells.
The KV gene family encodes more than 30 proteins that form the subunits of K⁺ channels, varying in gating and permeation properties, subcellular distribution, and expression patterns.
Functional KV channels assemble as tetramers of pore-forming alpha subunits (KV1–KV4) and accessory KV-subunits that modify gating properties.
KV beta.3 is an accessory K⁺ channel protein that regulates the activity of the pore-forming alpha subunit and alters the functional properties of Kv1.5.
KV beta.3 localizes to the cytoplasm and is expressed in the brain, with highest expression in the cerebellum and weakest in the frontal and temporal lobes.
No KV beta.3 expression is detected in the heart, spinal cord, lung, liver, kidney, pancreas, placenta, or skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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