Thermo Fisher Scientific WEE2 Polyclonal Antibody
WEE2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 WEE2 내부 영역 유래 합성 펩타이드를 면역원으로 사용하였으며, 액상 형태로 제공됩니다. 세포 주기 조절 및 난자 감수분열 연구에 활용 가능합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human WEE2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556093 |
Target Information
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300).
Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage by phosphorylating CDK1 at Tyr-15, leading to inhibition of CDK1 activity and prevention of meiotic reentry.
Also required for metaphase II exit during egg activation by phosphorylating CDK1 at Tyr-15 to ensure exit from meiosis in oocytes and promote pronuclear formation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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