Thermo Fisher Scientific Phospho-HCK (Tyr522) Polyclonal Antibody
HCK 단백질의 Tyr522 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 인간 및 생쥐 시료에 반응. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HCK (Accession P08631), corresponding to amino acid residues around phosphorylated Tyr522 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816909 |
Product Specific Information
This antibody detects endogenous levels of Hck only when phosphorylated at Tyr522.
Target Information
Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in some forms of leukemia.
HCK (Alias: DKFZp686D0638) is a protein-tyrosine kinase predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to activation of the respiratory burst and may play a role in neutrophil migration and degranulation.
Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in two isoforms with different subcellular localization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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