Thermo Fisher Scientific Filensin Monoclonal Antibody (FIL-7B10)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Frozen) (IHC (F))

1:400

-

Product Specifications

Species Reactivity

Bovine, Human, Sheep

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

FIL-7B10

Immunogen

Human and bovine lens filament enriched fraction (plasma membrane cytoskeleton complex). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Filensin,uniProtId:Q12934-1,ncbiNodeId:9606,antigenRange:1-665,antigenLength:665,antigenImageFileName:MA1-25031_Filensin_Q12934-1_House_mouse.svg,antigenImageFileNamePDP:MA1-25031_Filensin_Q12934-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

15mM sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2064881

Product Specific Information

Recommended positive controls: bovine lens.

MA1-25031 will not react with mouse, rat, or chicken.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.