Thermo Fisher Scientific Filensin Monoclonal Antibody (FIL-7B10)
Filensin 단백질을 인식하는 마우스 단클론 항체(FIL-7B10)로, Western blot 및 동결 절편 면역조직화학(IHC-F)에 적합. 소, 인간, 양에 반응하며, 마우스·쥐·닭에는 반응하지 않음. 단백질 구조 연구 및 수정체 세포 분화 연구용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:400 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Sheep |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FIL-7B10 |
| Immunogen | Human and bovine lens filament enriched fraction (plasma membrane cytoskeleton complex) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2064881 |
Product Specific Information
- Recommended positive control: Bovine lens
- MA1-25031 will not react with mouse, rat, or chicken.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (phakinin) and filensin, are expressed only after fiber cell differentiation has begun. Both proteins form a structurally unique cytoskeletal element called the beaded filament (BF).
Mutations in this gene can cause autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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