Thermo Fisher Scientific MBP Monoclonal Antibody (22)
MBP 단백질을 표적하는 mouse monoclonal antibody (Clone 22). WB, IHC, ICC 등 다양한 응용 가능. Human, Mouse, Rat 반응성. Unconjugated 형태로 제공되며, 연구용으로만 사용.
- 카탈로그번호
- MA125034
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Zebrafish |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 22 |
| Immunogen | Full length human MBP protein (UniProt ID: P02686-1, range: 1–304 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Tissue culture supernatant |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_794987 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. MBP-related transcripts are also found in bone marrow and the immune system. These arise from the long MBP gene, also known as Golli-MBP, which includes three additional upstream exons.
Alternative splicing from Golli and MBP transcription start sites produces two sets of MBP-related transcripts and gene products:
- Golli-MBP transcripts: contain unique Golli exons spliced in-frame with MBP exons, encoding hybrid proteins with N-terminal Golli and MBP sequences.
- Classic MBP transcripts: contain only MBP exons, producing the well-characterized myelin basic proteins.
This gene structure is conserved among species, suggesting that MBP is an integral part of the Golli transcription unit, important for gene regulation and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA1-25034_MBP_P02686-1_House_mouse.svg, MA1-25034_MBP_P02686-1_House_mouse_PDP.jpeg)
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