Thermo Fisher Scientific POLD3 Polyclonal Antibody
Thermo Fisher Scientific의 POLD3 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western blot과 ICC/IF에 사용 가능합니다. Affinity chromatography로 정제된 고품질 항체로 DNA 복제 및 수리 관련 연구에 적합합니다. 액상 형태로 -20°C에서 보관합니다.
- 카탈로그번호
- PA5106652
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human POLD3 (Accession Q15054), corresponding to amino acid residues D412–F462 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854320 |
Product Specific Information
Antibody detects endogenous levels of total POLD3.
Target Information
DNA replication, recombination, and repair processes essential for genomic stability require exonucleases. During replication, exonucleases process Okazaki fragments, while in repair they excise damaged DNA and correct mismatches. These functions involve DNA polymerase families (alpha, beta, delta, epsilon). DNA polymerase delta and epsilon are multisubunit enzymes interacting with PCNA. DNA polymerase delta 3 (POLD3, p66) is a 466 amino acid nuclear protein crucial for DNA polymerase delta function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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