
Thermo Fisher Scientific TrkA (extracellular) Polyclonal Antibody, Atto 633
Atto 633 형광 표지된 TrkA (extracellular) 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응. IHC(F) 적용 가능하며 항원 친화 크로마토그래피로 정제됨. 동결건조 형태로 제공되며 -20°C에서 보관. 신경영양 인자 수용체 연구용.
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Thermo Fisher Scientific TrkA (extracellular) Polyclonal Antibody, Atto 633
Applications and Tested Dilution
- Immunohistochemistry (Frozen) (IHC (F)): 1:50
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)ETMRHG(S)LRLNQPTH, corresponding to amino acid residues 342–356 of rat TrkA, extracellular, 2nd immunoglobulin-like domain |
| Conjugate | Atto™ 633 |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
- Ships as lyophilized powder at room temperature.
- Store at -20°C upon arrival.
- Reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
- For long-term storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10000 × g, 5 min).
Target Information
NTRK1 (TRKA) is a member of the neurotrophic factor family essential for mammalian nervous system development and maintenance. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and MAPK pathway members, leading to cell differentiation. Mutations in TrkA are associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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