Thermo Fisher Scientific GCH1 Polyclonal Antibody
Human GCH1 단백질을 표적으로 하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. IHC(P)에서 5 µg/mL 농도로 검증됨. 합성 펩타이드(aa 150-162)를 면역원으로 사용. 액상 형태, 0.5 mg/mL 농도, TBS buffer(pH 7.3) 보관. 연구용 전용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (GKVHIGYLPNKQ) corresponding to internal amino acids of GCH1 (aa 150–162) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983501 |
Product Specific Information
- Predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate.
BH4 is an essential cofactor required by aromatic amino acid hydroxylases and nitric oxide synthases.
Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia.
Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(본 제품 관련 항원 이미지: PA5-18885_GCH1_P30793-1_Goat.svg, PA5-18885_GCH1_P30793-1_Goat_PDP.jpeg)
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