Thermo Fisher Scientific MA2 Polyclonal Antibody
Thermo Fisher Scientific MA2 Polyclonal Antibody는 인간 및 랫트 시료에 반응하는 Rabbit IgG 항체로, Western Blot과 ELISA에 적합합니다. 재조합 단백질을 면역원으로 사용하며, 높은 순도(affinity chromatography 정제)와 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5117001
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA (ELISA)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–140 of human PNMA2 (NP_0091881) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.26 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901631 |
Product Specific Information
- Positive Samples: 293T, Jurkat, Rat brain
- Immunogen sequence:
MALALLEDWC RIMSVDEQKS LMVTGIPADF EEAEIQEVLQ ETLKSLGRYR LLGKIFRKQE NANAVLLELL EDTDVSAIPS EVQGKGGVWK VIFKTPNQDT EFLERLNLFL EKEGQTVSGM FRALGQEGVS PATVPCISPE
Target Information
In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a paraneoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a “brain-testis-cancer” gene related to other paraneoplastic syndromes and tumors.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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