Thermo Fisher Scientific ERK3 Monoclonal Antibody (4E8)
ERK3 단백질을 인식하는 Mouse monoclonal antibody(4E8)로, Human 시료에 반응합니다. Western blot, Flow cytometry, ELISA에 적합하며 비결합형 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E8 |
| Immunogen | Purified recombinant fragment of human ERK3 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154495 |
Product Specific Information
MA5-15837 targets ERK3 in indirect ELISA, FACS, and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human ERK3 expressed in E. coli.
MA5-15837 detects ERK3, which has a predicted molecular weight of approximately 105 kDa.
Target Information
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, closely related to mitogen-activated protein kinases (MAP kinases).
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), are activated through phosphorylation cascades and act as integration points for multiple biochemical signals.
This kinase is localized in the nucleus and is activated in fibroblasts upon treatment with serum or phorbol esters.
Tissue specificity: Highest expression in skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney, and skin fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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