Thermo Fisher Scientific HSP60 Monoclonal Antibody (3G8)
HSP60 단백질을 검출하기 위한 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC/IF, Flow cytometry, ELISA 등 다양한 응용에 적합. 사람, 마우스, 비인간 영장류, 랫트 시료에 반응. 비결합(Unconjugated) 형태로 제공되며, 냉장 또는 냉동 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G8 |
| Immunogen | Purified recombinant fragment of human HSP60 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155172 |
Product Specific Information
MA5-15836 targets HSP60 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with human, mouse, non-human primate, and rat samples.
The immunogen is a purified recombinant fragment of human HSP60 expressed in E. coli.
MA5-15836 detects HSP60 with a predicted molecular weight of approximately 61 kDa.
Target Information
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system and is essential for the folding and assembly of newly imported proteins in mitochondria.
The gene is adjacent to a related family member, and the region between the two genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified.
Mutations in this gene cause autosomal recessive spastic paraplegia 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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